Here's a piece of info I found on a professional pool/hot-tub website, this should solve your question:
"This depends on the size of the spa and the average daily bather load. Water should be checked three time per week for those using chlorine, bromine or a mineral purifier. Also a water sample should be taken to the dealer for analysis one time per month. If your spa cleaner is good then you have to change water only once in a month."