Most people don't have lockers in their homes.
What is the difference between locker at home and school?
This is a strange question. If you had a locker at home similar to the one at school, these would be the differences; the school and the school board own all lockers and can enter then at any time to do a legal search. If you damage your school locker, you must pay for the damage.
At home, the parents' rules apply, regardless of what they may be.